The Computational Biology Department (CBD) is a division within the School of Computer Science at Carnegie Mellon University in Pittsburgh, Pennsylvania, United States. It is located in the Gates-Hillman Center. Established in 2007 by Robert F. Murphy as the Lane Center for Computational Biology with funding from Raymond J. Lane and Stephanie Lane,[1] CBD became a department within the School of Computer Science in 2016.[2]

CBD faculty and students conduct research in genomics,[3][4] systems biology,[5] and biological imaging.[6][7] Its faculty have served as president of the National Science Foundation,[8] president of the International Society of Advanced Cytometry,[9] and as a member of the National Institutes of Health Council of Councils;[10] they have won awards such as the Overton Prize,[11] a Guggenheim Fellowship,[12] the Okawa Award,[13] a United States Air Force Young Investigator Award,[14] and a Presidential Young Investigator Award.[15]

As part of the HHMI-NIBIB Interfaces Initiative,[16] CBD received funding from Howard Hughes Medical Institute[17] and the National Institute of Biomedical Imaging and Bioengineering (NIBIB)[18] to develop an interdisciplinary Ph.D. program in computational biology with the University of Pittsburgh, which was founded as the Joint CMU-Pitt Ph.D. Program in Computational Biology in 2005.[19] This program is currently receiving training support through a National Institutes of Health T32 Training Grant.[20] CBD is the home of the B.S. in Computational Biology,[21] one of the four B.S. degree programs within Carnegie Mellon School of Computer Science. The Computational Biology undergraduate program is ranked as one of the top 3 programs by US News.[22]

CBD is the home of an NIH Center for the HuBMAP Integration, Visualization & Engaging (HIVE) Initiative[23] led by Ziv Bar-Joseph and an NIH Center for Multiscale Analysis of 4D Nucleome Structure and Function by Comprehensive Multimodal Data Integration[24] led by Jian Ma.

Notable faculty

Notable meetings hosted

  • RECOMB 2014[25]
  • Great Lakes Bioinformatics Conference 2013 (joint with University of Pittsburgh)[26]
  • Automated Personal Genome Analysis (APGA) 2013[27]
  • Bioimage Informatics 2010[28]

Degree programs

References

  1. ^ (CMU), Carnegie Mellon University. "Sept. 20: Carnegie Mellon Establishes Ray and Stephanie Lane Center for Computational Biology - Carnegie Mellon University". www.cmu.edu. Retrieved 2016-03-14.
  2. ^ (CMU), Carnegie Mellon University. "Sept. 22: Computational Biology Becomes Department in Carnegie Mellon's School of Computer Science - Carnegie Mellon University". www.cmu.edu. Retrieved 2016-03-14.
  3. ^ "Computational Method Dramatically Speeds Up Estimates Of Gene Expression, CMU, UMD Researchers Report | Carnegie Mellon School of Computer Science". www.cs.cmu.edu. Retrieved 2016-03-15.
  4. ^ Patro, Rob; Mount, Stephen M.; Kingsford, Carl (2014-05-01). "Sailfish enables alignment-free isoform quantification from RNA-seq reads using lightweight algorithms". Nature Biotechnology. 32 (5): 462–464. arXiv:1308.3700. doi:10.1038/nbt.2862. ISSN 1087-0156. PMC 4077321. PMID 24752080.
  5. ^ Kanfi, Yariv; Naiman, Shoshana; Amir, Gail; Peshti, Victoria; Zinman, Guy; Nahum, Liat; Bar-Joseph, Ziv; Cohen, Haim Y. (March 2012). "The sirtuin SIRT6 regulates lifespan in male mice". Nature. 483 (7388): 218–221. Bibcode:2012Natur.483..218K. doi:10.1038/nature10815. PMID 22367546.
  6. ^ Naik, Armaghan W.; Kangas, Joshua D.; Sullivan, Devin P.; Murphy, Robert F. (2016-02-03). "Active machine learning-driven experimentation to determine compound effects on protein patterns". eLife. 5: e10047. doi:10.7554/eLife.10047. PMC 4798950. PMID 26840049.
  7. ^ "Scientists' Robotically Driven System Could Reduce Cost of Discovering Drug and Target Interactions | Carnegie Mellon School of Computer Science". www.cs.cmu.edu. Retrieved 2016-03-15.
  8. ^ "Subra Suresh Biography". www.nsf.gov. Retrieved 2016-03-15.
  9. ^ "Past Presidents - ISAC-NET". isac-net.org. Archived from the original on 2016-03-06. Retrieved 2016-03-29.
  10. ^ "Murphy Appointed to NIH Council of Councils | Carnegie Mellon School of Computer Science". www.cs.cmu.edu. Retrieved 2016-03-29.
  11. ^ "2012 Overton Prize: Ziv Bar-Joseph". www.iscb.org. Retrieved 2016-03-15.
  12. ^ Carnegie Mellon. "Jian Ma Wins Guggenheim Fellowship - News - Carnegie Mellon University". Archived from the original on 2020-05-22.
  13. ^ "Carbonell Wins Okawa Prize". www.scs.cmu.edu. Retrieved 2016-03-15.
  14. ^ "Air Force invests more than $14M for 2010 Young Investigators Research Program". www.wpafb.af.mil. Archived from the original on 2016-04-13. Retrieved 2016-03-15.
  15. ^ "NSF Award Search: Award#8351364 - Presidential Young Investigator Award". www.nsf.gov. Retrieved 2016-03-29.
  16. ^ "HHMI-NIBIB Interfaces Initiative". HHMI.org. Archived from the original on 2016-03-12. Retrieved 2016-03-14.
  17. ^ "Institute News: HHMI Awards $10 Million for Interdisciplinary Graduate Education". HHMI.org. Retrieved 2016-03-14.
  18. ^ "NIBIB Invests in Interdisciplinary Graduate Research Training". www.nibib.nih.gov. Retrieved 2016-03-14.
  19. ^ "Carnegie Mellon Press Release: September 6, 2005". www.cmu.edu. Archived from the original on April 9, 2016. Retrieved 2016-03-14.
  20. ^ "Project Information - NIH RePORTER - NIH Research Portfolio Online Reporting Tools Expenditures and Results". projectreporter.nih.gov. Retrieved 2016-03-15.
  21. ^ a b "B.S. in Computational Biology | Computational Biology Department". Computational Biology Department | Carnegie Mellon University. Retrieved 2017-02-07.
  22. ^ "Best Undergraduate Bioinformatics/Biotechnology Programs". Archived from the original on 2021-08-25.
  23. ^ University, Carnegie Mellon. "Carnegie Mellon Will Help Build 3D Cellular Map of Human Body - News - Carnegie Mellon University". www.cmu.edu. Archived from the original on 2018-10-01. Retrieved 2021-07-31.
  24. ^ University, Carnegie Mellon. "Carnegie Mellon Heads New Center for Studying Structure of Cell Nucleus - News - Carnegie Mellon University". www.cmu.edu. Archived from the original on 2020-10-23. Retrieved 2021-07-31.
  25. ^ "RECOMB 2014 - April 2-5, Pittsburgh, Pennsylvania". murphylab.web.cmu.edu. Retrieved 2016-03-14.
  26. ^ "HOME". www.iscb.org. Retrieved 2016-03-14.
  27. ^ University, Carnegie Mellon. "Automated Personal Genome Analysis for Clinical Advisors: Challenges and Solutions -Computational Biology Department - Carnegie Mellon University". cbd.cmu.edu. Archived from the original on 2015-09-06. Retrieved 2016-03-29.
  28. ^ University, Carnegie Mellon. "Bioimage Informatics 2010-Computational Biology Department - Carnegie Mellon University". cbd.cmu.edu. Archived from the original on 2015-03-30. Retrieved 2016-03-14.
  29. ^ "Joint CMU-Pitt Ph.D. Program in Computational Biology (CPCB)". Retrieved 2018-03-06.
  30. ^ University, Carnegie Mellon. "M.S. in Computational Biology - Carnegie Mellon University". www.cmu.edu. Retrieved 2016-03-14.
  31. ^ "Biotechnology Innovation and Computation at Carnegie Mellon University". bic.cs.cmu.edu. Archived from the original on 2016-03-09. Retrieved 2016-03-14.
  32. ^ University, Carnegie Mellon. "Minor in Computational Biology-Computational Biology Department - Carnegie Mellon University". cbd.cmu.edu. Retrieved 2016-03-14.